Zinātniskās
publikācijas

“Plants”, 2021, 10, 1971

The effect of cultivation practises on both the phytochemical profile and biological activity
of aqueous ethanol extracts of Chelidonium majus L. was studied. Extracts were prepared from
aerial parts of the same plant population collected in the wild and grown under organic farming
conditions. Both qualitative and quantitative analyses of alkaloids and flavonoid derivatives were
performed by LC/MS methods, and the cytotoxicity of lyophilised extracts was studied in B16-
F10, HepG2, and CaCo-2 cells. Coptisine was the dominant alkaloid of extracts prepared from
wild-grown plants, whereas after cultivation, chelidonine was the most abundant alkaloid. The
total alkaloid content was significantly increased by cultivation.